云南省个旧市胃癌高危人群的筛查与随访结果分析

doi:10.11904/j.issn.1002-3070.2025.05.007

实用肿瘤学杂志 ›› 2025, Vol. 39 ›› Issue (5): 405-411.doi: 10.11904/j.issn.1002-3070.2025.05.007

云南省个旧市胃癌高危人群的筛查与随访结果分析

李芸, 史萍慧

昆明医科大学第五附属医院消化内科(个旧 661000)

收稿日期:2024-12-30 修回日期:2025-10-17 出版日期:2025-10-28 发布日期:2025-11-07
通讯作者: 史萍慧,E-mail:502867596@qq.com
作者简介:李芸,女,(1990—),硕士,主治医师,从事消化系统疾病相关的研究。
基金资助:
云南省教育厅科学研究基金项目资助(编号:2024J0323)

Analysis of gastroscopic screening and follow-up results among high-risk populations for gastric cancer in Gejiu City,Yunnan Province

LI Yun, SHI Pinghui

Department of Gastroenterology,The Fifth Affiliated Hospital of Kunming Medical University,Gejiu 661000,China

Received:2024-12-30 Revised:2025-10-17 Online:2025-10-28 Published:2025-11-07

摘要/Abstract

摘要： 目的分析2021—2023年个旧市胃癌高危人群筛查结果,为本市胃癌防治提供理论依据。方法采用问卷调查对个旧市40岁以上居民进行胃癌风险评估,对评估为胃癌高危人群者行胃镜检查及病理活检,并对筛查结果进行统计分析。结果 2021—2023年共评估居民24 391人,7 978人被评估为胃癌高危人群,其中完成胃镜及病理检查者2 473人,筛查率31.00%。共检出胃癌28例,高危人群胃癌检出率为1.13%;其中早期胃癌9例,早诊率46.43%。总体幽门螺杆菌(helicobacter pylori,HP)感染率为62.00%,且随胃黏膜病变程度加重呈上升趋势(P＜0.001)。男性、少数民族与HP感染者的胃癌及癌前病变检出率高于女性、汉族和非HP感染者,差异均有统计学意义(P＜0.05)。随访结果显示,重度萎缩性胃炎中有1例(2.08%)进展为早期胃癌,低级别上皮内瘤变中有2例(6.67%)进展至早期胃癌。结论本研究显示,个旧市胃癌高危人群的筛查检出率处于较高水平,但早期胃癌比例仍偏低,早诊率有待进一步提高。男性、少数民族及HP感染者为本地区胃癌防控的重点人群。HP感染可能与胃黏膜病变进展及胃癌发生密切相关,应加强相关干预。

关键词: 胃癌, 高危人群, 胃镜筛查, 幽门螺杆菌, 个旧市

Abstract: Objective The aim of this study was to analyze the gastroscopic screening results of high-risk populations for gastric cancer in Gejiu City from 2021 to 2023,and to provide theoretical basis for gastric cancer prevention and treatment in this city. Methods A questionnaire survey was conducted to assess the risk of gastric cancer among residents aged 40 and above in Gejiu City.Gastroscopy and pathological biopsy were performed on those assessed as high-risk for gastric cancer,and the screening results were statistically analyzed. Results From 2021 to 2023,a total of 24,391 residents were evaluated,of which 7,978 were at high-risk of gastric cancer.Among them,2,473 individuals completed gastroscopy and pathological examination,with a screening rate of 31.00%.Twenty-eight cases of gastric cancer were detected,and the detection rate of gastric cancer in high-risk populations was 1.13%;Among them,there were 9 cases of early-stage gastric cancer,with an early diagnosis rate of 46.43%.The overall infection rate of Helicobacter pylori(HP)was 62.00%,and it increased significantly with the severity of gastric mucosal lesions(P＜0.001).The detection rates of gastric cancer and precancerous lesions were significantly higher in males,ethnic minorities,and HP-infected individuals was higher than those in females,Han people,and non-HP-infected individuals,and the differences were statistically significant(P＜0.05).Following-up results showed that 1 case(2.08%)of severe atrophic gastritis progressed to early gastric cancer,and 2 cases(6.67%)of low-grade intraepithelial neoplasia progressed to early gastric cancer. Conclusion The detection rate of gastric cancer among high-risk populations in Gejiu City was relatively high,however the proportion of early-stage cases remained low,indicating that the rate of early diagnosis still needs to be improved.Males,ethnic minorities,and HP-infected individuals are key target groups for gastric cancer prevention and control in this region.HP infection may be closely related to the progression of gastric mucosal lesions and the occurrence of gastric cancer,and relevant interventions should be strengthened.

Key words: gastric cancer, high-risk population, gastroscopic screening, helicobacter pylori, Gejiu City

中图分类号:

R735.2

李芸, 史萍慧. 云南省个旧市胃癌高危人群的筛查与随访结果分析[J]. 实用肿瘤学杂志, 2025, 39(5): 405-411.

LI Yun, SHI Pinghui. Analysis of gastroscopic screening and follow-up results among high-risk populations for gastric cancer in Gejiu City,Yunnan Province[J]. Journal of Practical Oncology, 2025, 39(5): 405-411.

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云南省个旧市胃癌高危人群的筛查与随访结果分析

Analysis of gastroscopic screening and follow-up results among high-risk populations for gastric cancer in Gejiu City,Yunnan Province

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