Abstract: Objective The relationship between fever and the recent curative effect of transcatheter arterial chemoembolization(TACE)and the related factors of fever after transcatheter arterial chemoembolization in large hepatocellular carcinoma is discussed in this paper.Methods One hundred and twenty patients with large liver cancer were divided into two groups according to the fever after TACE.The fever in group A,and there was no fever in group B after TACE.The changes of the lesions in the two groups were compared after the first interventional treatment.The factors affecting the fever after TACE were analyzed.Results The CT was performed at about one and half month after the first intervention.The curative effects of A and B were evaluated by RECIST criteria.Two groups of CR,PR,SD,PD were 0,11.11%,71.11%,17.78% and 0,0,33.33%,66.67%,respectively.The difference of the efficiency of OR was statistically significant(P=0.049).The probability of fever of four types of iodine oil deposits are as follows:100%,93.33%,81.93%,0.Blood supply type,middle and severe hepatic arteriovenous fistula,the use of gelatin sponge,tumor necrosis,and the use of iodine oil were more than 25ml may be factors affecting postoperative fever.Conclusion The clinical symptoms of fever after TACE suggest that the lesion is well embolization and iodine oil deposit is good,and the lesion is not easy to progress,and short-term curative effect is better.The analysis of the factors that affect the postoperative fever may help to evaluate the curative effect of patients with large hepatocellular carcinoma.

Key words: Large hepatocellular carcinoma, Chemoembolization, Postembolization fever, Curative effect