Abstract: When the body is attacked by trauma and infection,the serum C-reactive protein(CRP)concentration which is produced by the liver will increase.CRP participates in the body′s humoral immunity through regulating the phagocytic cells to clear the pathogenic bacteria and necrotic tissue.The occurrence and development of malignant tumor is associated with complex inflammatory response pathway.Serum CRP concentration will change with the progress and remission of tumor.CRP is associated with differentiation of benign and malignant,the early diagnosis,the pathological stage,the lymph node metastasis,the organizational characteristics,the prognosis,and the treatment of malignant tumor.It is expected to be a clinical screening indicator of malignant tumor.

Key words: C-reactive protein, Malignant tumor, Early diagnosis, Prognosis