Abstract: Objective To observe the application effects of postoperative analgesia of ultrasound-guided transversus abdominis plane(TAP)block in radical resection of colorectal cancer patients.Methods Fifty patients undergoing radical resection of colorectal cancer in our hospital within nearly two years were divided into two groups,according to number table mehtod,25 cases in each group.Patients of group A were injected with 0.45% ropivacaine mesylate 20 mL in ultrasound-guided bilateral TAP after the end of surgery before extubation;the patients of group B were injected with the same amount of normal saline in ultrasound-guided bilateral TAP block,Postoperative patient-controlled intravenous analgesia with sufentanil was provided to all patients.The VAS score of two groups after operation record the postoperative dosage of sufentanil in 24h,pressing times of analgesia pump,the satisfaction of patients with postoperative analgesia and adverse reactions.Results The VAS score of group A(1.08±0.86),(1.60±0.71),(1.92±0.49),(2.28±0.61),(2.44±0.51)were lower than that of group B(1.88±0.73),(2.24±0.72),(2.68±0.56),(2.96±0.54),(3.24±0.44).The dosage of sufentanil in group A(53.20±1.39)μg vs. group B(59.18±2.82)μg,pressing times of analgesia pump,group A(10.40±2.78)vs. group B(22.36±5.63),the satisfaction of patients with postoperative analgesia,group A(9.12±0.78)vs. group B(7.52±0.77).There were 2 cases of postoperative nausea and vomiting in group B vs 8 cases in group A,The above-mentioned indexes difference had statistical significance except postoperative 4h score. The indicators of respiratory depression in the two groups did not occur.Conclusion The application of postoperative analgesia of ultrasound-guided transversus abdominis plane(TAP)block in radical resection of colorectal cancer patients,can reduce postoperative intravenous analgesic drug usage,decrease the incidence of adverse reactions induced by opioid drugs,and the analgesic effect is more effective with the positioning accuracy,convenient operation,less injury,high safety and suitable for clinical application.

Key words: Ultrasonography, Transversus abdominis plane block, Analgesia