14-3-3ζ与恶性肿瘤关系的研究进展

doi:10.11904/j.issn.1002-3070.2017.06.012

Abstract

Abstract: The 14-3-3 protein is a highly conserved acidic polypeptide family involved in intracellular signaling,protein transportation,cell proliferation,invasion,migration,and apoptosis.Many studies have shown that 14-3-3ζ has a high expression level in many malignant tumors.This paper introduces the structure of 14-3-3ζ,the biological function,and the development of the malignant tumor (breast cancer,lung cancer,hepatocellular carcinoma,glioma,head and neck neoplasms)related to the development of 14-3-3ζ and treatment of malignant tumor in order to provide valuable information and ideas.

Key words: 14-3-3ζ, Malignant tumors, Treatment

CLC Number:

HAN Xuejiao, LI Yanchun, SUN lichun, LU Hailing. Research progress of the relationship between 14-3-3ζ and malignant tumor[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(6): 543-547.

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Research progress of the relationship between 14-3-3ζ and malignant tumor

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