PRACTICAL ONCOLOGY JOURNAL ›› 2018, Vol. 32 ›› Issue (1): 42-46.doi: 10.11904/j.issn.1002-3070.2018.01.008

• Review • Previous Articles     Next Articles

Research progress on the relationship between microRNA-196a and tumor

XIN He, WANG Chuanzhuo, LIU Zhaoyu   

  1. Sheng Jing Hospital of China Medical University,Shenyang 110004,China
  • Received:2017-10-16 Online:2018-02-20 Published:2018-03-07

Abstract: As a member of the miRNA family, microRNA-196a (miR-196a) has received much attention in recent years. MiR-196a not only plays an important regulatory role in various biological processes, but it also shows that miR-196a also functions as oncogene in the tumorigenesis and progression. In recent studies, miR-196a is high expression in the serum, tissues and cells of patients with cancer, and can promote tumor cell proliferation, invasion and metastasis, inhibit tumor cell apoptosis and enhance tumor drug resistance. In this paper, we reviewed the research progress on the correlation between miR-196a and tumor based on the latest reports at domestics and abroad.

Key words: miR-196a, Tumor, microRNA

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