PRACTICAL ONCOLOGY JOURNAL ›› 2018, Vol. 32 ›› Issue (3): 267-270.doi: 10.11904/j.issn.1002-3070.2018.03.016

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The relationship between metformin and different molecular subtypes of breast cancer

LI Lin,LI Zhigao   

  1. Department of Oncology,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2018-01-07 Online:2018-07-10 Published:2018-07-10

Abstract: Metformin as the first-line medication for diabetes treatment can not only reduce blood sugar,but it also induces apoptosis in breast cancer cells.The effect and mechanism of metformin on various types of breast cancer are confirmed by in vitro and in vivo,and metformin can also co-treat breast cancer in neoadjuvant chemotherapy and radiotherapy.This article will review the progress of metformin in the treatment of breast cancer.

Key words: Metformin, Breast cancer, Treatment

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