Abstract: Objective The aim of this study was to analyze the incidence and mortality of female breast cancer in Yunnan province in 2016 and the change trend from 2011 to 2016,so as to provide a reference for breast cancer prevention and control.Methods Based on the data from the cancer registration and related population in Yunnan province from 2011 to 2016,these data were reviewed and evaluateed crg Tools 2.05 published by IARC and Excel 2007.The incidence,mortality,and standard rate of female breast cancer,cumulative rate of 0~74 years old,and truncated rate(35~64)years old were calculated.A Joinpoint 4.8 was used to calculate annual percentage change(APC)so as to comprehensively analyze the trend of incidence and death of female breast cancer.Results In 2016,the crude incidence of female breast cancer in Yunnan province was 28.95/100,000,accounting for 14.60% of all malignant tumors,ranking the first among female malignancies.The crude mortality rate was 6.25/100,000,accounting for 6.48% of malignant tumor deaths,ranking the fifth among female malignant tumor deaths.The crude incidence,China standard rate(ASR China),world standard rate(ASR World),cumulative rate(0~74 years old),and truncated rate(35~64 years old)of female breast cancer in rural areas were higher than those of urban areas.The crude mortality,ASR China,ASR World,truncated rate(35~64 years old)of female breast cancer in urban areas were higher than those of rural areas.In Yunnan province from 2011 to 2016,there were no statistically significant in of incideme APC and mortality for female breast cancer in all areas urban areas and rural areas(P＞0.05).Conclusion In 2016,the incidence and mortality of female breast cancer in Yunnan province were lower than the national average.The incidence in rural areas was higher than that in urban areas,and the mortality in urban areas was higher than that in rural areas.The ASR China incidence and mortality of female breast cancer remained basically unchanged from 2011 to 2016,and the prevention and treatment of breast cancer should be further strengthened according to the characteristics of female breast cancer incidence and death.

Key words: Female breast cancer, Incidence, Mortality, Annual percentage change, Yunnan