Abstract: Objective The objective of this study was to analyze the incidence and death of upper gastrointestinal cancer in the cancer registration areas of Shanxi province in 2016,and to provide evidence for prevention and control of upper gastrointestinal cancer. Methods The cancer registration data reported by 12 tumor registration areas of Shanxi in 2016 were sorted out and stratified by urban and rural areas and gender.The number of cases and deaths,the crude incidence and mortality,the cumulative rate(0~74 years old),age-specific incidence and mortality were calculated.The incidence and mortality were standardized by the 2000 China Census standard population composition(ASR China)and Segi′s World standard population composition(ASR World). Results In 2016,there were 2 940 new cases of upper gastrointestinal cancer and 2,135 deaths in the cancer registration areas of Shanxi province.The crude incidence of upper gastrointestinal cancer was 60.13/100,000(80.53/100,000 in male and 38.97/100,000 in female;39.38/100,000 in urban areas and 74.17/100,000 in rural areas),the population standardization rate in China was 41.91/100,000,the population standardization rate in World was 42.97/100,000,and the cumulative incidence rate for 0~74 years old was 5.61/100,000.The crude rate of death from upper gastrointestinal cancer of Shanxi in 2016 was 43.67/100,000(58.56/100,000 in males and 28.21/100,000 in females;31.67/100,000 in urban areas and 51.78/100,000 in rural areas),the standardized mortality rate in China was 29.94/100,000,the standardized mortality rate in World was 30.52/100,000,the cumulative mortality rate of 0~74 years old was 3.62/100,000.Overall,incidence and mortality of upper gastrointestinal cancer in rural areas were higher than those in urban areas.The incidence and mortality of upper gastrointestinal cancer in males were higher than females.After 40 years old,the incidence of upper gastrointestinal cancer was on the rise.The incidence peaks in the 80-year-old age group were in urban areas and 65-year-old in rural areas.The mortality of upper gastrointestinal cancer was at a low level before the 45-year-old age group,and then gradually increased with increasing age,and peaked in the 85+ years old age group. Conclusion Upper gastrointestinal cancer is the most common malignant tumor that threatens the health of residents in Shanxi province.Male population,people in rural areas,middle-aged and elderly population are the focus of cancer prevention and control in Shanxi province.Upper digestion cancer should be carried out in a targeted manner of cancer prevention and treatment work according to urban-rural and gender differences.

Key words: Shanxi province, Tumor registration, Upper gastrointestinal cancer, Incidence, Mortality