植物化学物γ-生育三烯酚抗癌活性与作用机制的研究进展

doi:10.11904/j.issn.1002-3070.2023.06.005

Abstract

Abstract: γ-Tocotrienol(γ-T3)is a common phytochemical belonging to a major subclass of natural vitamin E,mainly derived from palm oil and rice bran.Compared to saturated tocopherol(TOC),the γ-T3 side chain contains unsaturated bonds and forms isoprene chains.γ-T3 has therapeutic activity for various chronic diseases with broad potential applications,especially in inhibiting tumor proliferation and invasion.With deeply research,more and more evidence suggests that γ-T3 plays an important role in inhibiting cancer cell migration and metastasis,inducing tumor cell apoptosis,arresting cell cycle and regulating cancer-related signaling pathways.Therefore,this article will review the anti-cancer effects and mechanisms of γ-T3.

Key words: γ-Tocotrienol, Anti-cancer activity, Phytochemicals

CLC Number:

ZHU Hao, WANG Falin, SUN Wenguang, LIU Jiaren. Research progress on the anticancer activity and mechanism of phytochemical - gamma-tocotrienol[J]. Journal of Practical Oncology, 2023, 37(6): 485-490.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2023.06.005

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2023/V37/I6/485

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[1]	GUO Sijia, LIU Jiaren. Effects of phytochemicals in cancer chemoprevention [J]. Journal of Practical Oncology, 2020, 34(5): 460-465.
[2]	CHANG Xiaoxia, SONG Bingbing, LIU Jiaren. Research progress in phytochemicals for increasing sensitivity of tumor cells to chemotherapies [J]. PRACTICAL ONCOLOGY JOURNAL, 2019, 33(1): 67-72.

Research progress on the anticancer activity and mechanism of phytochemical - gamma-tocotrienol

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