维甲酸诱导蛋白在消化系统恶性肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2023.06.008

Abstract

Abstract: The Global Cancer Statistics Report in 2020 shows that the incidence and mortality of digestive system malignancies are high,but the mechanism is still unclear in the occurrence and development of digestive system malignancies.Retinoic acid-induced protein(RAI)is a kind of protein induced by retinoic acid,which is closely related to the proliferation,invasion and migration of digestive system malignant tumors.The expression of RAI series proteins in digestive system tumors is related to clinical prognosis.Overexpression or knockdown of RAI protein can affect the sensitivity of digestive system malignant tumors to targeted drug therapy.RAI protein may also be a specific target protein closely related to the occurrence and development of digestive system tumors.This article reviews the role and related mechanisms of RAI protein in the occurrence and development of malignant tumors in the digestive system,providing some references for early diagnosis,treatment and prognosis assessment of the disease.

Key words: Retinoic acid-induced protein, Malignant tumors of the digestive system

CLC Number:

R735

CHENG Jin, WANG Wei. Research progress on retinoic acid-induced proteins in malignant tumors of the digestive system[J]. Journal of Practical Oncology, 2023, 37(6): 502-506.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2023.06.008

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2023/V37/I6/502

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Research progress on retinoic acid-induced proteins in malignant tumors of the digestive system

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