Abstract: Objective To observe the inhibitory effect of TBA on H22 transplanted tumor in mice.Method H22 tumor bearing mice were used as model.There were 10 in each group.TBA was administered by oral in TBA high(0.50g/kg),middle(0.25g/kg)and low(0.13g/kg)dose group.0.5% sodium carboxymethyl cellulose solution 2mL/10g^-1 was administered by oral in control group.CTX 20mg/kg was injected intragastric in positive control group.The tumor bearing mice were administered once a day at fixed time and continuous administered for 10 days.Then,the tumor were weighted and tumor inhibition rate were observed in each group,the tumor cell morphology was observed by HE staining.Result The average tumor weight reduced in TBA groups,in which TBA 0.250g/kg group compared with the control group,the differences were significant(P＜0.05),the inhibitory rate of TBA 0.50g/kg,0.25g/kg and 0.13g/kg group were 24.83%,45.52% and 15.86% respectively.Conclusion TBA could inhibit H22 tumor growth of tumor bearing mice by oral administration.