铜依赖性细胞死亡及铜在乳腺癌治疗中的研究现状

doi:10.11904/j.issn.1002-3070.2023.02.017

Abstract

Abstract: Copper is a metal element involved in a variety of biological processes.Maintaining the balance of copper ions is an important condition for maintaining the health of body.Copper is related to the occurrence and development of many diseases,including malignant tumors."Cuprotosis" is a newly proposed cell death mode that depends on the accumulation of intracellular copper.Studies have shown that the dynamic balance of copper is related to the occurrence and development of breast cancer,and the research on copper in the treatment of breast cancer is also rising.This article mainly summarizes the mechanism of copper-dependent cell death and the research status of copper in breast cancer.

Key words: Copper, Cuprotosis, Copperion carrier, Breast cancer treatment

CLC Number:

R737.9

WEN Shichao, WANG Jingxuan. Research status of copper-dependent cell death and copper in breast cancer[J]. Journal of Practical Oncology, 2023, 37(2): 185-189.

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Research status of copper-dependent cell death and copper in breast cancer

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