6A甲基化修饰在肿瘤中的作用

doi:10.11904/j.issn.1002-3070.2020.05.018

Abstract

Abstract: N6-methyladenosine(m6A)modification,as a part of epigenetic research,is one of the most common RNA modifications,and has attracted more and more attention in recent years.m6A methylation modification is dynamically regulated by methyltransferase,demethylase and reading protein.A large number of studies have shown that m6A methylation modification can affect the occurrence and development of cancer by regulating the biological functions related to cancer.This article briefly introduces m6A methylation modification and reviews the role of m6A methylation modification in different tumors.

Key words: m6A methylation, Methyltransferase, Demethylase, Reading protein

CLC Number:

R730.5

LI Hui, PANG Da. The role of m6A methylation modification in tumors[J]. Journal of Practical Oncology, 2020, 34(5): 480-484.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2020.05.018

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2020/V34/I5/480

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The role of m6A methylation modification in tumors

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