Journal of Practical Oncology ›› 2021, Vol. 35 ›› Issue (1): 87-90.doi: 10.11904/j.issn.1002-3070.2021.01.018

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Research progress of lncRNA-HEIH in tumor

FENG Yuxin,ZHU Chunrong   

  1. The First Affiliated Hospital of Soochow University,Suzhou 215006,China
  • Published:2021-01-30

Abstract: Long non-coding RNAs(lncRNA)are a new class of non-coding RNAs that participate in the biological processes of many diseases.lncRNA-HEIH(High expression in hepatocellular carcinoma,HEIH)regulates tumor proliferation,migration,invasion,apoptosis and drug resistance through different mechanisms.Its expression level is related to the clinicopathological characteristics of tumors and plays a key role in tumor occurrence and development.This article briefly introduces the concept of lncRNA-HEIH,and systematically reviews its biological functions and molecular mechanisms in hepatocellular carcinoma,lung cancer,breast cancer,colorectal cancer,endometrial cancer and other malignant tumors.The prospect of lncRNA-HEIH is considered as a potential biomarker and a new target for cancer treatment.

Key words: lncRNA, lncRNA-HEIH, Tumor, Biomarker

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