miR-21在食管癌中的研究进展

doi:10.11904/j.issn.1002-3070.2017.03.018

实用肿瘤学杂志 ›› 2017, Vol. 31 ›› Issue (3): 277-280.doi: 10.11904/j.issn.1002-3070.2017.03.018

miR-21在食管癌中的研究进展

靳晶综述，贺宇彤审校

河北医科大学第四医院肿瘤研究所(石家庄 050011)

收稿日期:2017-01-04 出版日期:2017-06-28 发布日期:2017-07-04
通讯作者: 贺宇彤,E-mail:doc106@163.com
作者简介:靳晶,男,(1986-),硕士,研究实习员,从事肿瘤流行病学的研究

Research progress of miR-21 in esophageal cancer

JIN Jing,HE Yutong

Cancer Institute,The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China

Received:2017-01-04 Online:2017-06-28 Published:2017-07-04

摘要/Abstract

摘要： 食管癌是一种常见的恶性肿瘤,发病率高,预后差。miR-21在食管癌患者的癌组织、血液、唾液中均表达上调,其表达异常与食管癌发生发展密切相关。miR-21主要通过调控与肿瘤相关的靶基因发挥作用,尤其在食管癌的诊断、治疗及预后中有重要的临床应用价值。

关键词: 食管癌, microRNA, miR-21, 综述文献

Abstract: Esophageal cancer is a common malignancy with a high incidence and a poor prognosis.MiR-21 is up-regulated in cancer tissues,blood and saliva of esophageal cancer patients.Its abnormal expression is closely related to the development of esophageal cancer.MiR-21 plays an important role in the regulation of tumor-related target genes,especially in the diagnosis,treatment and prognosis of esophageal cancer.

Key words: Esophageal cancer, microRNA, miR-21, Review literature

中图分类号:

R735.1

靳晶综述，贺宇彤审校. miR-21在食管癌中的研究进展[J]. 实用肿瘤学杂志, 2017, 31(3): 277-280.

JIN Jing,HE Yutong. Research progress of miR-21 in esophageal cancer[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(3): 277-280.

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miR-21在食管癌中的研究进展

Research progress of miR-21 in esophageal cancer

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