实用肿瘤学杂志 ›› 2017, Vol. 31 ›› Issue (5): 425-430.doi: 10.11904/j.issn.1002-3070.2017.05.007

• 临床应用 • 上一篇    下一篇

双源CT双能量扫描融合三维重建技术在诊断胃癌及淋巴结中应用的研究

姜智允, 李鹏飞, 隋林, 尚乃舰   

  1. 哈尔滨医科大学附属肿瘤医院(哈尔滨 150081)
  • 收稿日期:2016-11-14 出版日期:2017-10-28 发布日期:2017-10-24
  • 通讯作者: 尚乃舰,E-mail:shangnaijian@126.com
  • 作者简介:姜智允,男,(1990-),硕士研究生,从事双源CT在临床中应用的研究

Application of dual-source CT dual-energy scanning fusion 3D reconstruction in gastric cancer and lymph nodes

JIANG Zhiyun, LI Pengfei, SUI Lin, SHANG Naijian   

  1. Department of Radiology,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2016-11-14 Online:2017-10-28 Published:2017-10-24

摘要: 目的 本研究探讨双源CT双能量增强扫描获得的参数能否区分胃癌病灶与正常胃壁,以确定病变范围,提高早期胃癌符合诊断率,精准N分期。方法 通过西门子Somatom Definition Flash双源CT对术前胃癌患者进行双能量增强扫描,将采集的数据经Syngo.Via软件分析及三维重建,获得胃癌病灶、正常胃壁、转移淋巴结与非转移淋巴结的绝对碘值、标准化碘值及虚拟单能量能谱曲线的斜率并记录,结合术后病理结果,应用统计学方法分析判断两两之间的差异。结果 胃癌病灶的绝对碘值为(3.329±0.812)g/L,标准化碘值为(64.006±17.450)%,虚拟单能量能谱曲线的斜率为(-2.916±1.3227),与正常胃壁的绝对碘值(1.563±0.708)g/L,标准化碘值(37.122±16.267)%,虚拟单能量能谱曲线的斜率(-1.621±1.4028)比较,均存在统计学差异(P<0.05);转移淋巴结的绝对碘值为(2.968±0.547)g/L,标准化碘值为(63.597±14.633)%,虚拟单能量能谱曲线的斜率为(-2.532±0.753),与非转移淋巴结绝对碘值(1.465±0.408)g/L,标准化碘值(35.240±14.357)%,虚拟单能量能谱曲线的斜率(-1.378±0.726)比较,均存在统计学差异(P<0.05)。结论 双源CT双能量扫描获得的参数结合三维重建技术有助于确定病变范围,提高早期胃癌的符合诊断率,区分转移淋巴结与非转移淋巴结以提高N分期的准确率。

关键词: 双源CT双能量扫描, 三维重建, 绝对碘值, 标准化碘值, 虚拟单能量能谱曲线斜率

Abstract: Objective The objective of this study was to determine the lesion range between gastric cancer lesions and normal gastric wall,improve the early diagnosis of gastric cancer rate,distinguish between metastatic lymph nodes and non-metastatic lymph nodes,and accurate N staging by dual-source CT double-energy enhanced scan parameters.Methods The dual energy enhanced scan of patients with preoperative gastric cancer was performed by Siemens Somatom Definition Flash dual-source CT.The collected data were analyzed by Syngo.Via software and reconstructed three-dimensionally to obtain the absolute iodine of gastric cancer,normal gastric wall,metastatic lymph node and non-metastatic lymph node value,standardized iodine value and virtual single energy spectrum curve of the slope to combine with postoperative pathological results.The use of statistical methods was to determine the difference between the post-and preoperation.Results The absolute iodine values(IC)were(3.329±0.812)g/L in the gastric cancer lesion and(64.006±17.450)% for the standard iodine values(NIC).The slope of the virtual single energy spectrum curve was-2.916±1.3227,IC(1.563±0.708)g/L in the normal gastric wall.The NIC were(37.122±16.267)% and-1.621±1.4028 for the slope of the virtual single energy spectrum curve.They were significantly statistical difference(P<0.05).The IC of metastatic lymph nodes were(2.968± 0.547)g/L,(63.597±14.633)% for the NIC and(-2.532 ± 0.753)for the slope of the virtual single energy spectrum curve.The IC of non-metastatic lymph nodes were(1.465±0.408)g/L,(35.240±14.357)% for the NIC and(-1.378±0.726)for the slope of the virtual single energy spectrum curve.They also had significantly statistical difference(P<0.05).Conclusion Dual-source CT dual-energy scan combined with three-dimensional reconstruction technique can help to determine the lesion range,improve the diagnostic rate of early gastric cancer,distinguish between metastatic and non-metastatic lymph nodes,and improve the accuracy of N staging.

Key words: Dual-energy of dual-source CT scanning, Three-dimensional reconstruction, IC, NIC, The slope of spectrum curve

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