实用肿瘤学杂志 ›› 2021, Vol. 35 ›› Issue (3): 282-286.doi: 10.11904/j.issn.1002-3070.2021.03.017

• 综述 • 上一篇    下一篇

脂肪因子Omentin-1与肿瘤相关性的研究

潘红艳, 李爱萍 综述, 李强 审校   

  1. 深圳大学总医院内分泌科(深圳 518051)
  • 收稿日期:2020-08-26 修回日期:2020-10-19 出版日期:2021-06-28 发布日期:2021-06-22
  • 通讯作者: 潘红艳,E-mail:yichunphy@163.com
  • 作者简介:潘红艳,女,(1970-),博士,主任医师,从事脂肪因子作用机制的研究。
  • 基金资助:
    黑龙江省普通高校骨干教师创新项目(编号:1054G024)

Research progress of the correlation between adipokine omentin-1 and tumor

PAN Hongyan, LI Aiping, LI Qiang   

  1. Department of Endocrine,Shenzhen University General Hospital,Shenzhen 518051,China
  • Received:2020-08-26 Revised:2020-10-19 Online:2021-06-28 Published:2021-06-22

摘要: Omentin-1是脂肪因子Omentin在血液循环中的主要形式。研究发现,Omentin-1与消化系统肿瘤、泌尿系统肿瘤、女性肿瘤及神经系统肿瘤等多种肿瘤相关,但其在不同类型的肿瘤中表现出高度异质性。Omentin-1参与多个肿瘤相关的信号通路及抑癌因子的调解,其在肿瘤发生发展中所起的作用和相关机制的研究越来越多。

关键词: 脂肪因子, Omentin-1, 恶性肿瘤

Abstract: Omentin-1 is the main form of adipokine omentin in blood circulation.It has been found that Omentin-1 is associated with many kinds of tumors,such as digestive system tumor,urinary system tumor,female tumor and nervous system tumor,but it shows high heterogeneity in different types of tumors.Omentin-1 is involved in the regulation of multiple tumor related signaling pathways and tumor suppressor factors.There are more and more studies on the role of Omentin-1 in tumorigenesis and development and related mechanisms.

Key words: Adipokines, Omentin-1, Malignant tumor

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