Abstract: Objective To compare the prognosis efficacy between total laparoscopic gastrectomy and ordinary gastric cancer for familial gastric cancer.Methods The selected 60 patients with ordinary gastric cancer from August 2012 to 2014 in our hospital as the control group,the same period in familial gastric cancer of 40 patients were chosen as control group.All patients were performed by total laparoscopic gastrectomy.Results The operative time,blood loss,postoperative discharge time compared in the two groups were showed no significant differences.However,the postoperative hospital stayed in the observation group and the number of lymph nodes were significantly longer more than the control group(P＜0.001).The postoperative pulmonary infection,intestinal obstruction,abdominal infection,anastomotic leakage,anastomotic bleeding and other complications in the observation group were significantly lower than in the control group(P＜0.001).After the investigation,the dysphagia,pain,anxiety,physical appearance,dry mouth scores in the observation group were significantly higher(P＜0.001).Conclusion Familial gastric cancer has unique clinical and pathological features,Compared to ordinary stomach,the total laparoscopic gastrectomy treatment of familial gastric cancer need more lymph nodes dissection,it can cause more complications,it has some impacts on the quality of life for patients.

Key words: Familial gastric cancer, Total laparoscopic gastrectomy, Complications, Quality of life