Abstract: Objective Our retrospective study is aimed to discuss the relationship between the curve changes of T lymphocyte subsets before and after the operation and the infectious complications after radical resection of gastric cancer.Methods Clinical data of patients with gastric cancer received treatment at Central Hospital of Panjin City,Liaoning Province from 2012 to 2014 were retrospectively analyzed.The enrolled patients were divided into two groups according to the infectious complications,observe group(patients with infectious complications)and control group(patients without infectious complications).The results of T lymphocyte subsets in two groups were compared.Results A total of 70 patients was retrospective analyzed,including 33 pationts in observe group and 37 pationts in control group.At the 4th day after operation,the levels of CD3,CD4 in the observe group were obviously lower than those in control group.There was no statistical difference at the other time points.At the 4th and 9th day after operation,the levels of CD8,CD4/CD8 rate in the observe group were obviously lower than those in control group.There was no statistical difference at the other time points.Conclusion There is remarkable relationship between the curve changes of T lymphocyte subsets before or after the operation and the incidence of infectious complications after radical resection of gastric cancer.