PRACTICAL ONCOLOGY JOURNAL ›› 2016, Vol. 30 ›› Issue (1): 61-65.doi: 10.11904/j.issn.1002-3070.2016.01.013

• Review • Previous Articles     Next Articles

Research progress of cellular immunotherapy for hematological malignancies

HUANG Juanjuan, WANG Wenxin, CAO Fenglin   

  1. Department of Hematology,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China
  • Received:2015-11-01 Online:2016-02-28 Published:2016-02-25

Abstract: In recent years,considerable progress has been made in the treatment of hematologic malignancies.However,most patients will eventually relapse and suffer from severe side effects caused by chemotherapy or radiation.Thus,as a well tolerated,safe,effective and innovative therapy,adoptive cellular immunotherapy emerges at this very moment.This therapy can kill tumors or control recurrence by reinfusing the in vitro amplificated or treated immune effective cells into the patients.It has been actively used in the treatment of various hematological malignancies and achieved significant effects,which brings hope for more and more patients with relapsed or refractory hematological diseases.

Key words: Hematological malignancies, Cellular immunotherapy, CIK cells, NK cells, CART

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