PRACTICAL ONCOLOGY JOURNAL ›› 2011, Vol. 25 ›› Issue (4): 340-343.doi: 10.3969/j.issn.1002-3070.2011.04.010

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Intensity modulated radiation therapy for gerontal cervical cancer patients

QI Chunlei,YANG Baojuan,CHENG Haiyan,ZHANG Yunyan   

  1. Department of Gynecology Radiotherapy,The Third Affiliated Hospital,Harbin Medical University,Harbin 150081
  • Received:2011-04-19 Online:2011-04-25 Published:2012-02-21

Abstract: Objective To discuss the clinical significance of intensity modulated radiation therapy(IMRT)in gerontal cervical cancer.Methods Sixty patients of gerontal cervical cancer in our study.Thirty patients were treated by IMRT,and thirty were treated by CRT.We compared short-term efficacy and complications between two groups.Results The tumour regression rates were 86.7% for IMRT group and 90.0% for CRT group(P>0.05)respectively.The 1-year and 2-year survival rates were 86.7% and 73.3% in IMRT group respectively,which were no significant difference compared with those in CRT group(80.0% and 63.3%),(P>0.05).Compared with CRT group,the doses and volume of small intestine,rectum,bladder in IMRT group were significantly decreased(P<0.05).The incidence rates of acute gastrointestinal tract and urinary system radiation reaction in IMRT group were significantly lower than those in the CRT group(P<0.05).The incidences of long-term radiation proctitis,cyctitis in IMRT group were significantly lower than those in the CRT group(P<0.05).Conclusion Compared with CRT in gerontal cervical cancer,IMRT did not improve local tumor control rate and the recent survival rate,but significantly reduced the response to acute and chronic radiation.

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