Abstract: Radiotherapy is the main treatment for nasopharyngeal carcinoma.The intensity modulated radiation therapy is one of the most ideal radiotherapy technology for nasopharyngeal carcinoma.Local recurrence and distant metastasis are still the main reasons responded to the radiation fails.Therefore,chemoradiotherapy has become the most recommended treatment for nasopharyngeal carcinoma(NPC),and the synchronous chemoradiotherapy is a widely accepted joint model.Neoadjuvant chemotherapy shows significant advantages comparing to concurrent chemoradiotherapy in reducing the adverse reactions,while it is uncertain whether the follow-up maintenance chemotherapy can improve total survival.The understanding of targeted drugs in chemoradiotherapy is still in early stage,but the result is worth looking forward to.In addition,novel treatments and concepts,including immune therapy and biological chemotherapy,are attracting more and more attention.