SALL4基因在人恶性肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2016.05.019

Abstract

Abstract: Malignant tumor is a serious threat to human health and its pathogenesis is complex,which caused by interaction of a variety of carcinogenic factors in the human body.SALL4 gene is a kind of newly discovered gene and it plays an important role in function of embryonic stem cell due to its protein transcription factor with C2H2 zinc finger domain.Studies found that this gene mutation often Results in occurrence of malignant tumor.This paper will summarize the molecular mechanism of SALL4 in the occurrence and development of malignant tumor and its diagnosis and treatment on malignant tumor.

Key words: Proto-oncogene, SALL4, Tumor

CLC Number:

R73.37

WANG Jue, ZHANG Huijie. Research progress of SALL4 gene in malignant tumor disease[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(5): 477-480.

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Research progress of SALL4 gene in malignant tumor disease

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