PRACTICAL ONCOLOGY JOURNAL ›› 2017, Vol. 31 ›› Issue (6): 554-558.doi: 10.11904/j.issn.1002-3070.2017.06.014

• Review • Previous Articles     Next Articles

Advances in gene expression profiling of metastases from unidentified primary tumor

HAN Qian, LIN Lianjun, LIU Xinmin   

  1. Department of Geriatric,Peking University First Hospital,Beijing 100034,China
  • Received:2017-04-10 Online:2017-12-28 Published:2018-01-02

Abstract: Primary lesions unknown metastatic cancer (CUP)is a class of histopathologically confirmed metastases.However,a variety of clinical diagnosis and treatment can not clear the primary tumor.The identification of tumor primary site is the first step in the diagnosis of CUP.The histopathology,immunohistochemistry and PET /CT are commonly used clinical diagnosis and treatment.Gene expression profiling technique is a new method for the diagnosis of primary tumor in recent years.It has high diagnostic accuracy,sensitivity and specificity,and is expected to achieve individual treatment of patients with CUP.

Key words: Cancer of unknown primary sites(CUP), Gene expression profiling(GEP), Progress in diagnosis

CLC Number: