Journal of Practical Oncology ›› 2020, Vol. 34 ›› Issue (4): 357-361.doi: 10.11904/j.issn.1002-3070.2020.04.012

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Application progress of liquid biopsy in the diagnosis of colorectal cancer

LI Hengzhen, ZHANG Yanqiao   

  1. Department of Gastrointestinal Medical Oncology,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2019-12-19 Published:2020-08-17

Abstract: Colorectal cancer(CRC),as the third most common cancer in the world,is one of important cause of human death.At present,the diagnostic methods for CRC are still being improved.Liquid biopsy,as an emerging non-invasive biopsy technology,has attracted widespread attention.Liquid biopsy mainly analyzes specific components of biological source liquid,which mainly include circulating tumor cells,circulating tumor DNA,cell free DNA,exosomes,tumor-educated platelets,and circulating tumor-associated microparticles.This article reviews the latest application research of the above biological source liquid specific components in the diagnosis of CRC.

Key words: Colorectal cancer, Liquid biopsy, Diagnosis

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