Journal of Practical Oncology ›› 2022, Vol. 36 ›› Issue (5): 411-416.doi: 10.11904/j.issn.1002-3070.2022.05.004

• Clinical Research • Previous Articles     Next Articles

Clinical analysis of 319 patients with nasopharyngeal carcinoma in Nantong City

CHEN Haizhen1, CHEN Jianguo1,2, WANG Gaoren1, ZHU Jian2, PAN Minxia3, GE Xiaoxia1, HUANG Sheng1, XU Rongfang1, SHEN Aiguo1   

  1. 1. Nantong Tumor Hospital/Affiliated Tumor Hospital of Nantong University,Nantong 226361,China;
    2. Qidong Liver Cancer Institute/Qidong People's Hospital/Affiliated Qidong Hospital of Nantong University;
    3. Nantong Health College of Jiangsu Province
  • Received:2022-03-11 Revised:2022-10-08 Online:2022-10-28 Published:2022-11-10

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Abstract: Objective The aim of this study was to analyze the clinical data of nasopharyngeal carcinoma cases in Nantong Tumor Hospital from 2002 to 2017,to understand the distribution and epidemic characteristics of nasopharyngeal carcinoma in Nantong,and to provide reference information for early diagnosis and screening of nasopharyngeal carcinoma and the formulation of comprehensive prevention and treatment measures. Methods The case data of 319 nasopharynx cancer patients were collected in the tumor registration database of Nantong Tumor Hospital from January 2002 to December 2017,and the distribution of age,sex,symptoms,course of disease,number of hospitalizations and pathological types etc.of nasopharyngeal carcinoma were statistically analyzed. Results Among 319 nasopharynx cancer patients,221 were male(69.28%)and 98 female(30.72%).The minimum age was 16 years old,the maximum age was 83 years old,and the median age was 55 years old.The patients were mainly 40-69 years old.The median duration of hospitalization was 5.02 months,and those over 6 months accounted for 50.47%.Among the clinical symptoms,43.57% were nasal symptoms,and 40.44% were accompanied by neck tumors.In TNM staging,124 cases(38.87%)were T1-T2,103 cases(32.29%)were T3-T4,33 cases(10.34%)were N0,176 cases(N1-N2)(55.17%),and 48 cases(15.05%)were distal recurrence and metastasis(M1).The clinical staging was mainly in the middle and late stages:Phase Ⅲ was the most common(115 cases,36.05%),followed by phase IV(78 cases,37.62%).The most common type of pathological tissue was non-keratinizing undifferentiated carcinoma(98.43%).Distribution of hospitalizations times:20.06% were hospitalized once,53.61% were hospitalized 2-5 times,and the average of hospitalization time was(4.48±3.71).The 5-year observed survival rates of early cases and middle and late cases were 77.50% and 72.96%,respectively,with statistical significance(P＜0.05). Conclusion The majority of hospitalized nasopharynx cancer patients are males,middle-aged and elderly,and the majority of non-keratinized undifferentiated cancer patients are middle and late stage patients.Early diagnosis and treatment of nasopharynx cancer should be attention.

Key words: Nasopharyngeal carcinoma, Hospitalization, Staging, Nantong

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