Abstract: Objective The Objective of this study was to analyze the screening rate of urban high-risk breast cancer population in Hefei from 2014 to 2017 and its influencing factors. Methods A cluster sampling method was used to conduct a questionnaire survey on cancer risk factors and an assessments of breast cancer risk factors among residents aged 40 to 74 years old in 7 districts of Hefei city.Breast ultrasonography was performed on high-risk groups aged 40 to 44 years old for breast cancer,and breast ultrasound combined with breast mammography were performed on high-risk groups aged 45 to 74 years old for breast cancer.The screening rate of high-risk subjects were calculated,compared the differences of breast cancer screening rates in different characteristic groups,and analyzed the relevant influencing factors of breast cancer screening rate. Results A total of 45,563 breast cancer high-risk assessment were completed from 2014 to 2017,including 8,249 cases of breast cancer high-risk group.A total of 4,622 cases of breast cancer high-risk group participated in breast cancer screening,and the breast cancer screening rate was 56.03%.There was a significant time difference in the screening rate of breast cancer high-risk groups for breast cancer,with the highest screening rate(61.70%)in 2015—2016 and the lowest screening rate(51.73%)in 2016—2017.The results of multivariate logistic regression analyses showed that breast cancer high-risk groups with passive smoking exposure history,drinking,mental trauma,history of benign breast diseases,family history of breast cancer and family history of ovarian cancer were more likely to participate in clinical screening of breast cancer(P＜0.001).Compared with 2014—2015,the high-risk groups of breast cancer in 2015—2016 were more likely to receive breast cancer screening(P＜0.001).Compared with those with education level of primary school and below,middle school with education level were more likely to accept breast cancer screening(P＜0.01).The high-risk group of breast cancer with regular physical exercise,menarche age ≥12 years old,and breast feeding history was more difficult to accept breast cancer screening(P＜0.01). Conclusion Education level,physical exercise,menarche age,lactation history,passive smoking exposure history,alcohol drinking,mental trauma,history of benign breast disease,family history of breast or ovarian cancer are the influencing factors for screening rate of breast cancer.Publicity and education should be focused on the above influencing factors to increase the screening rate of high-risk groups for breast cancer.

Key words: Breast cancer, Screening rate, Influencing factors, City, Hefei