铜死亡在肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2024.01.008

Abstract

Abstract: Copper is an indispensable trace element in living organisms and maintains at a certain level in cells under physiological conditions.Cuprotosis is a unique,copper-dependent cell death.It is an extremely important type of regulated cell death(RCD)and is different from other forms of cell death currently known.More and more studies have shown that cuprotosis has a non-negligible impact on the metabolic pathway transition,signaling pathway transduction,and protein processing and modification of tumor cells.Cuprotosis-related lncRNAs are also widely used to predict tumor prognosis.Cuprotosis can inhibit tumor cell growth and serve as a potential target for controlling drug resistance and disease recurrence.This article reviews the mechanism of cuprotosis in the development and progression of tumor cells.

Key words: Cuprotosis, Tumor, Cell death, Regulated cell death

CLC Number:

R737.9

GAO Yuan, TANG Yuhan, WANG Lu, ZHAO Wenhui. Research progress of cuprotosis in tumors[J]. Journal of Practical Oncology, 2024, 38(1): 50-54.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2024.01.008

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2024/V38/I1/50

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Research progress of cuprotosis in tumors

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