关键词: 肿瘤登记, 甲状腺癌, 发病率, 死亡率, 时间趋势, 云南

Abstract: Objective The aim of this study was to understand the incidence and mortality characteristics,and prevalence trends of thyroid cancer in the cancer registration areas of Yunnan province from 2012 to 2016,and to provide suggestions for the prevention and treatment of thyroid cancer. Methods The incidence and death of thyroid cancer cases(ICD-10 coded as C73)in Yunnan Cancer Registry from 2012 to 2016 were collected and sorted out.The incidence,mortality,standardized incidence,standardized mortality,truncation rate(35~64 years old),cumulative rate(0~74 years old),and annual percentage change(APC)of thyroid cancer were analyzed by urban and rural areas. Results The crude incidence of thyroid cancer from 2012 to 2016 in Yunnan cancer registration areas was 8.74/100,000.The China standardized rate was 7.51/100,000,the World standardized rate was 6.59/100,000,the cumulative rate was 0.64%,and the truncation rate was 13.89/100,000.The crude thyroid cancer death rate was 0.68/100,000,The China standardized rate was 2.44/100,000,the world standard rate was 2.39/100,000,the cumulative rate was 0.27%,and the cut-off rate was 3.74/100,000.The age-specific incidence was at a low level of 0~20 years old,and increased rapidly with age after 20 years old,peaks in the 50- years old group,and gradually decreased after 55 years old.The age-specific mortality was at a low level of the 0~40 years old age group,and increased rapidly after the 40 years old age group,reaching two peaks in the 65-years old and 85+ years old age groups,respectively.From 2012 to 2016,the total incidence of thyroid cancer,the women incidence,the crude incidence of thyroid cancer in rural areas(APC was 43.7%,42.3%,and 37.4%,respectively)and the standardized rate(APC was 42.4%,40.9%,and 36.5%,respectively)showed upward trend(P＜0.05). Conclusion Thyroid cancer has become one of the common malignant tumors in Yunnan province,and the incidence is increasing rapidly year by year.Research on its risk factors should be strengthened and comprehensive prevention and treatment should be carried out.

Key words: Cancer registration, Thyroid cancer, Incidence, Mortality, Time Trend, Yunnan