2022—2024年江苏省淮安市淮河流域癌症早诊早治项目上消化道癌筛查效果评价

doi:10.11904/j.issn.1002-3070.2026.01.003

实用肿瘤学杂志 ›› 2026, Vol. 40 ›› Issue (1): 16-21.doi: 10.11904/j.issn.1002-3070.2026.01.003

2022—2024年江苏省淮安市淮河流域癌症早诊早治项目上消化道癌筛查效果评价

沈欢¹, 缪丹丹¹, 孙中明¹, 陈思红², 包雨晴³, 梅冬蒙¹, 潘恩春¹

1.淮安市疾病预防控制中心慢病科(淮安 223001);
2.淮安市洪泽区疾病预防控制中心慢病科;
3.淮安市涟水县疾病预防控制中心慢病科

收稿日期:2025-10-10 修回日期:2026-01-30 出版日期:2026-02-28 发布日期:2026-02-27
通讯作者: 潘恩春,E-mail:hypec@163.com
作者简介:沈欢,男,(1991—),硕士,主管医师,从事慢性病防治相关的研究。
基金资助:
江苏省预防医学科研课题项目(编号:Ym2023086);淮安市自然科学研究计划(联合专项)卫生健康类项目(编号:HABL202265)

Evaluation of the effectiveness of upper gastrointestinal cancer screening in the cancer early diagnosis and treatment project of Huaihe River Basin of Huai′an City,Jiangsu Province from 2022 to 2024

SHEN Huan¹, MIAO Dandan¹, SUN Zhongming¹, CHEN Sihong², BAO Yuqing³, MEI Dongmeng¹, PAN Enchun¹

1. Department of Chronic Disease,Huai′an Center for Disease Control and Prevention,Huai′an 223001,China;
2. Department of Chronic Disease,Hongze District Center for Disease Control and Prevention;
3. Department of Chronic Disease,Lianshui County Center for Disease Control and Prevention

Received:2025-10-10 Revised:2026-01-30 Online:2026-02-28 Published:2026-02-27

摘要/Abstract

摘要： 目的分析2022—2024年江苏省淮安市淮河流域癌症早诊早治项目上消化道癌筛查结果及成本效果,为进一步优化区域上消化道癌防控策略提供科学依据。方法采用整群抽样方法,选取2022—2024年参加淮安市淮河流域癌症早诊早治项目上消化道癌筛查的40~75岁居民作为研究对象。对目标人群开展健康因素调查并进行高危评估,动员高危人群接受内镜检查及病理诊断。比较不同特征参与者的高危率、依从率、检出率和早诊率。核实筛查成本资料,开展卫生经济学评价。结果 2022—2024年共完成26 081人的健康因素调查,评估出上消化道癌高危人群14 629人,高危率56.09%;其中共有10 128人进行了内镜检查,依从率为69.23%,女性依从率高于男性(P＜0.001)。共检出上消化道癌阳性病例137例,检出率为1.35%,男性检出率高于女性(P＜0.001);40~49岁年龄组未检出阳性病例,70~74岁检出率最高。早期病例82例,早诊率为59.85%。成本效果分析显示,每检出1例阳性病例和早期病例的成本分别为35 423.36元和59 182.93元,早期发现成本系数(early detection cost index,EDCI)为0.57,提示筛查项目具有较好的卫生经济学价值。结论江苏省淮安市开展的淮河流域癌症早诊早治项目上消化道癌筛查具有良好的成本效果,后续应加强男性人群健康教育以提高其内镜筛查依从性,同时重点关注50岁以上人群的筛查工作,以进一步提高上消化道癌筛查效果。

关键词: 上消化道癌, 筛查, 淮河流域, 成本效果分析

Abstract: Objective The aim of this study was to analyze the results and cost-effectiveness of upper gastrointestinal cancer screening under the Cancer Early Diagnosis and Treatment Project in the Huaihe River Basin of Huai′an City,Jiangsu Province from 2022 to 2024,and to provide a scientific basis for further optimizing regional upper gastrointestinal cancer prevention and control strategies. Methods A cluster sampling method was employed to select residents aged 40 to 75 who participated in the upper gastrointestinal cancer screening under the Cancer Early Diagnosis and Treatment Project in the Huaihe River Basin of Huai′an City from 2022 to 2024 as the study subjects.Health factor surveys and high-risk assessments were conducted among the target population,and high-risk individuals were mobilized to undergo endoscopy and pathological diagnosis.The high-risk rate,compliance rate,detection rate,and early diagnosis rate of participants with different characteristics were compared.Screening cost data were verified,and a health economic evaluation was conducted. Results From 2022 to 2024,a total of 26,081 health factor surveys were completed,identifying 14,629 high-risk individuals for upper gastrointestinal cancer,with a high-risk rate of 56.09%.Among them,a total of 10,128 individuals underwent endoscopy,with a compliance rate of 69.23%,which was higher in females than that in males(P＜0.001).A total of 137 positive cases of upper gastrointestinal cancer were detected,with a detection rate of 1.35%,which was higher in males than that in females(P＜0.001).No positive cases were detected in the 40-49 age group,with the highest detection rate in the 70-74 age group.There were 82 early-stage cases,with an early diagnosis rate of 59.85%.The cost-effectiveness analysis showed that the cost per detected positive case and early-case was 35,423.36 yuan and 59,182.93 yuan,respectively.The early detection cost index(EDCI)was 0.57,indicating that the screening project had good health economic value. Conclusions The upper gastrointestinal cancer screening under the Cancer Early Diagnosis and Treatment Project in the Huai′an City,Jiangsu Province,has good cost-effectiveness.In the future,health education for the male population should be strengthened to improve their compliance with endoscopic screening,and special attention should be paid to screening for individuals over 50 years old to further enhance the effectiveness of upper gastrointestinal cancer screening.

Key words: upper gastrointestinal cancer, screening, Huaihe River Basin, cost-effectiveness analysis

中图分类号:

R735

沈欢, 缪丹丹, 孙中明, 陈思红, 包雨晴, 梅冬蒙, 潘恩春. 2022—2024年江苏省淮安市淮河流域癌症早诊早治项目上消化道癌筛查效果评价[J]. 实用肿瘤学杂志, 2026, 40(1): 16-21.

SHEN Huan, MIAO Dandan, SUN Zhongming, CHEN Sihong, BAO Yuqing, MEI Dongmeng, PAN Enchun. Evaluation of the effectiveness of upper gastrointestinal cancer screening in the cancer early diagnosis and treatment project of Huaihe River Basin of Huai′an City,Jiangsu Province from 2022 to 2024[J]. Journal of Practical Oncology, 2026, 40(1): 16-21.

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2022—2024年江苏省淮安市淮河流域癌症早诊早治项目上消化道癌筛查效果评价

Evaluation of the effectiveness of upper gastrointestinal cancer screening in the cancer early diagnosis and treatment project of Huaihe River Basin of Huai′an City,Jiangsu Province from 2022 to 2024

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