PRACTICAL ONCOLOGY JOURNAL ›› 2014, Vol. 28 ›› Issue (6): 561-564.doi: 10.11904/j.issn.1002-3070.2014.06.017

• Review • Previous Articles     Next Articles

Progress on relationship between gastric cancer and tumor microenvironment

WANG Tao,ZHENG Yongguang,FAN Kangwu,LI Yumin   

  1. Department of VIP Surgery,The Second Hospital of Lanzhou University,Lanzhou 730000,China
  • Received:2014-07-10 Online:2014-12-28 Published:2015-01-08

Abstract:

Gastric cancer is the fourth malignancies and the second cancer-related mortality rate in the world.Although the incidence of gastric cancer has declined in the past few decades,it is still a serious health problem.Tumor microenvironment plays an important role in tumorigenesis and progression.The main components of gastric cancer include tumor associated macrophages、lymphocytes、cancer-associated fibroblasts、angiogenesis factors,cytokines,gastric microenvironment and the mechanism of action of chemokines.In this review,the correlation between tumor microenvironment and GC is discussed.

Key words: Gastric cancer, Tumor microenvironment, Helicobacter pylori

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