PRACTICAL ONCOLOGY JOURNAL ›› 2016, Vol. 30 ›› Issue (6): 543-546.doi: 10.11904/j.issn.1002-3070.2016.06.013

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Progress in association between autophagy and cancer

REN Tingting,XING Ying,MENG Qingwei   

  1. Department of Oncology,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China
  • Received:2016-08-26 Online:2016-12-31 Published:2016-12-27

Abstract: Autophagy is a highly conservative biological behavior in eukaryotic cells.This dynamic process involves "wrapping" cytoplasmic components and combining with lysosomes in cells for catabolism.Autophagy can not only take part in maintaining homeostasis,but also be closely related with tumor development and resistant.Therefore,autophagy is a potential target for antitumor drug resistant.Specific inhibition of autophagy in cancer cells combined with chemotherapy is expected to be an effective cancer treatment strategy.

Key words: Autophagy, Tumor, Chemotherapy drug resistance

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