CyclinD1表达与泌尿系统肿瘤关系的研究进展

doi:10.11904/j.issn.1002-3070.2016.03.014

Abstract

Abstract: Cyclin D is the most closely relationship with tumor,and it is currently known one of the subtypes of cyclins.CyclinD1,as a positive regulatory factor,has an important role in the process of cell cycle,especially in cell proliferation and division.CyclinD1 is unusually up-regulated in lots of human cancers.CyclinD1 is a recently discovered protein which is highly expressed in the urinary tumors,and its expression in tumors is associated with a more aggressive phenotype,prognosis and recurrence.Therefore,the research of the target point to CyclinD1 in the urinary tumors may provide a new method for the therapy to urinary tumors.

Key words: CyclinD1, Urothelial carcinoma, Renal carcinoma, Prostatic carcinoma, Penile carcinoma

CLC Number:

R737.1

NIU Defang,CUI Yan,CHEN Hui. Progress in the research of CyclinD1 in urinary tumor[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(6): 547-550.

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Progress in the research of CyclinD1 in urinary tumor

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