XBP-1在肿瘤发生发展中的研究进展

doi:10.11904/j.issn.1002-3070.2017.01.014

Abstract

Abstract: X-box binding protein-1(XBP-1)is a newly found protein that plays significant roles in protein folding and endoplasmic reticulum construction.The expression of XBP-1 is widely displayed in various kinds of tumor and is shown to take part in tumorigenesis and tumor progression.This review briefly summarizes the biology of XBP-1 and focuses on recent findings concerning its role in immune evasion,tumorigenesis,development of cancer,angiogenesis,hypoxia,invasion and metastasis.

Key words: XBP-1, Immune escape, Angiogenesis, Cancer

CLC Number:

NI Shouhua, YUE Xiaolong, WU Jin. The transcription factor X-box binding protein-1 in tumorigenesis and development of cancer[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(1): 65-68.

References

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The transcription factor X-box binding protein-1 in tumorigenesis and development of cancer

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