热休克蛋白70在肝细胞癌中的研究进展

doi:10.11904/j.issn.1002-3070.2017.06.009

Abstract

Abstract: Heat shock protein 70(HSP70)is a highly conserved polypeptide protein,which plays an important role in protein homeostasis,apoptosis,invasion and cell signaling transduction.Many studies have shown that the expression level of HSP70 is closely related to the development and progression of tumor,which is a low expression in normal tissues and the overexpression in tumor tissue.Hepatocellular carcinoma(HCC)is concealed,and the related study reported that the expression of HSP70 can be used as a sensitive biological index for the diagnosis and differential diagnosis for early HCC,and also affects the treatment and prognosis of patients with HCC.This article will summary the relationship between the expression of HSP70 and HCC.

Key words: Heat shock protein 70, Hepatocellular carcinoma, Diagnosis, Prognosis

CLC Number:

R735.7

ZHAO Lingyun, QI Lunan, YOU Xuemei. Research progress of heat shock protein 70 in hepatocellular carcinoma[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(6): 528-532.

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Research progress of heat shock protein 70 in hepatocellular carcinoma

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