HOX基因与妇科肿瘤的研究进展

doi:10.11904/j.issn.1002-3070.2018.02.010

Abstract

Abstract: The homeobox(HOX)gene is a special type of transcriptional regulator that plays an important role in physiological regulation mechanisms such as embryonic development,cell growth,differentiation and migration.Recent studies have found that HOX gene expression is abnormal and affects the occurrence and development of tumor.This review summarizes the progress of HOX gene and gynecologic oncology including cervical cancer,endometrial cancer and ovarian cancer,and the instruction and application of HOX gene in the treatment of cancer.We are making the guiding direction of exploring HOX gene through summarizing the existed research reports in order to alleviate the pain of gynecological cancer patients.

Key words: HOX, Cervical carcinoma, Endometrial cancer, Epithelial ovarian cancer

CLC Number:

R737

BI Qiling, ZHOU Lihong, HAN Yimin. Research progress of HOX gene and gynecologic tumor[J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(2): 140-143.

References

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Research progress of HOX gene and gynecologic tumor

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