纳米材料在肿瘤光动力治疗中的应用

doi:10.11904/j.issn.1002-3070.2018.03.011

Abstract

Abstract: Photodynamic therapy(PDT)utilizes a photodynamic reaction,that is,a photosensitizer(PSs)activated by light of a specific wavelength in the presence of molecular oxygen to produce a reactive oxygen species including singlet oxygen to kill tumor cells.PDT has the advantages of less trauma,high selectivity,low toxicity,and good applicability.However,the lack of an ideal PS,lack of light source tissue penetration depth,and hypoxia of tumor tissue have been severely restricted in clinical practice.Nanomaterials can solve the above problems encountered in photodynamic therapy,and have recently been widely used in PDT of tumor.Thus,this review will summarize the application progress of nanoparticles in PDT.

Key words: Malignant tumors, Photodynamic therapy, Nanoparticles

CLC Number:

R730.5

ZHOU Jie, CHEN Yu, CHEN Daozhen. Application of nanoparticles in photodynamic therapy of tumor[J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(3): 245-249.

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Application of nanoparticles in photodynamic therapy of tumor

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