不同麻醉方式对老年肺癌患者术后认知功能的影响

doi:10.11904/j.issn.1002-3070.2018.05.009

Abstract

Abstract: Objective The aim of this study was to evaluate effects of general anesthesia and general anesthesia combined with paravertebral block(PVB)anesthesia on hemodynamics and postoperative cognitive function in elderly patients undergoing lung thoracotomy.Methods A total of 100 elderly patients who underwent lung cancer surgery in our hospital for the past two years were selected and aged 65~75 years old.The patients were randomly divided into the control and the observation groups.The control group was treated with general anesthesia(n=50).The observation group was applied to general anesthesia combined with PVB anesthesia(n=50).The hemodynamic changes of control and observation groups were observed and recorded during and after anesthesia.The Mini-mental State Examination(MMSE)score,eye opening time,extubation time and response time were compared before and after surgery.Results The hemodynamics changes in the observation group during and after operation were more stable than that in the control group(P＜0.05).There was no significant difference in the MMSE scores between the control and observation groups before operation.The MMSE scores in patients after surgery in the observation group were higher than that in the control group(P＜0.05).In the control group,the eye opening time was(34.8±10.5)min,extubation time was(34.1±6.5)min,and response time was(38.9±9.6)min.The observation group was(30.2±10.3)min,(30.3±7.4)min,and(33.6±9.6)min,in eye opening time,extubation time and response time,respectively.They were significantly decreased in the observation group than those in the control group(P＜0.05).Conclusion Compared to general anesthesia,the general anesthesia combined with PVB anesthesia has a smaller impact on the patient′s vital signs and less chance of postoperative cognitive impairment.

Key words: General anesthesia, Paravertebral block, Lung cancer, Cognitive function

CLC Number:

R734.2

ZHONG Xuelai, YANG Haili, WANG Guonian. Effects of different anesthesia methods on postoperative cognitive function in elderly patients with lung cancer[J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(5): 432-436.

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Effects of different anesthesia methods on postoperative cognitive function in elderly patients with lung cancer

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