PRACTICAL ONCOLOGY JOURNAL ›› 2018, Vol. 32 ›› Issue (6): 567-570.doi: 10.11904/j.issn.1002-3070.2018.06.017

• Review • Previous Articles     Next Articles

Research progress in zinc finger proteins in colon cancer

AI Lianjie, PIAO Daxun   

  1. Department of Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
  • Received:2018-10-01 Online:2018-12-28 Published:2018-12-27

Abstract: Colon cancer is one of the common malignant tumors in the world, and its mechanism of occurrence and development is complex and has not yet been fully elucidated.The incidence and mortality of colon cancer are high, and the prognosis is poor, which possess a serious threat to human health.Zinc finger protein is a kind of transcription factor with zinc finger domain, which is widely involved in various biological activities in humans, especially in notable regulating gene expression.Zinc finger protein plays an important role in the molecular regulation of colon cancer development and is expected to the development of colon cancer as a new target of targeted therapy.In this paper, the recent research progress of zinc finger protein and colon cancer is reviewed.

Key words: Zinc finger protein, Colon cancer, Transcription factor, Gene expression

CLC Number: