Journal of Practical Oncology ›› 2020, Vol. 34 ›› Issue (1): 93-96.doi: 10.11904/j.issn.1002-3070.2020.01.018

• Review • Previous Articles    

Research progress in the effects of intestinal microbes on colorectal cancer patients by metagenomics

LI Zhijie, ZHAO Qi, WU Huaxing   

  1. Endoscopy Room,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2019-08-06 Revised:2019-11-06 Online:2020-02-28 Published:2020-02-20

Abstract: Human gut microbes have received increasing attention in the medical community,and they have a great role not only in human health,but also in the occurrence and development of human diseases.The link between microbes and cancer,especially between the gut microbiota and intestinal tumors,is constantly being discovered.Metagenomics,as an important research method in microbial research,plays an increasingly important role in the study of microbial and colorectal cancer.In recent years,the study of gut microbiota by metagenomics has provided new insights into the development and progression of colorectal cancer,which emphasize the importance of host-microbe and microbial interactions in cancer microbiota.This article reviews the relationship between gut microbiota and colorectal cancer through metagenomics,and is expected to open up new opportunities for prevention,diagnosis and treatment of cancer.

Key words: Intestinal microbes, Colorectal cancer, Metagenomics

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