Journal of Practical Oncology ›› 2020, Vol. 34 ›› Issue (6): 554-559.doi: 10.11904/j.issn.1002-3070.2020.06.014

• Review • Previous Articles     Next Articles

Research progress of miR-409-3p and tumor

ZUO Rui1,2, JIN Lu1,2, LIU Li1,2, LIU Xiaojia1,2, ZHAO Pengyu1,2, XIANG Xiaoyan1,2   

  1. 1. Department of Burn and Plastic Surgery,The Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China;
    2. North Sichuan Medical College
  • Received:2020-02-09 Revised:2020-03-26 Online:2020-12-28 Published:2020-12-23

Abstract: microRNA is a type of endogenous non-coding small RNA.It binds to the 3′UTR of its target gene at the post-transcriptional level,thereby regulating a variety of organism process.miR-409-3p belongs to a large family of microRNA.With the deepening of research,more and more evidence shows that there is abnormal expression of miR-409-3p in tumors,which is also closely related to the occurrence,development and prognosis of tumors.miR-409-3p and has received extensive attention about its important role in various processes such as tumor cell proliferation,apoptosis,angiogenesis,migration,invasion and the development of drug resistance.In recent years,MiR-409-3p may become a research hot spot as a new circulating marker.This article reviews the research progress of miR-409-3p in tumors.

Key words: microRNA, miR-409-3p, Tumor, Diagnosis, Treatment, Prognosis

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