Journal of Practical Oncology ›› 2021, Vol. 35 ›› Issue (1): 50-54.doi: 10.11904/j.issn.1002-3070.2021.01.010

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Research progress of long non-coding RNA SNHG3 in malignant tumor

ZHENG Zhiyuan,QU Guofan   

  1. Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Published:2021-01-30

Abstract: Long non-coding RNA(lncRNA)is a kind of RNA molecule whose sequence length is more than 200 nucleotides and cannot encode a protein.In recent years,more and more studies have pointed out that lncRNA is closely related to the diagnosis,prevention,treatment and prognosis of tumors,and has great value in the clinical application of malignant tumors.Small nucleolar RNA host gene-3(SNHG3)plays a carcinogenic role in promoting cell proliferation,invasion and regulating epithelial-mesenchymal transition(EMT),suggesting that SNHG3 can be used as a biomarker to evaluate the malignancy of tumors.This article reviews the research progress of the relationship between SNHG3 and malignant tumors in recent years,and discusses the current situation and prospects of SNHG3 in the treatment of malignant tumor.

Key words: Small nucleolar RNA host gene-3, Long non-coding RNA, Malignant tumor

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