非编码RNA在膀胱癌中的研究进展

doi:10.11904/j.issn.1002-3070.2020.06.016

Abstract

Abstract: Bladder cancer is one of the most common cancers in the world.Although the prognosis of patients to a certain extent has been improved by surgery combined with chemotherapy and radiotherapy,the prognosis of most patients with muscle-invasive bladder cancer is still poor.Moreover,the exact mechanism and key regulators of bladder cancer are unclear.Recent studies have shown that some non-coding RNAs are dysregulated in bladder cancer and play crucial roles in the development of bladder cancer.More importantly,non-coding RNA can be used as a biomarker for the diagnosis and prognosis of bladder cancer.This review aims to summarize recent research progress,which indicate the regulatory mechanisms for three types of non-coding RNAs including miRNA,lncRNA,and circRNA in bladder cancer,and their potential roles as biomarkers for clinical diagnosis or prognosis.

Key words: Bladder cancer, miRNA, lncRNA, circRNA

CLC Number:

R737.14

LI Rongdi, LI Xuedong. Research progress of non-coding RNA in bladder cancer[J]. Journal of Practical Oncology, 2020, 34(6): 565-570.

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http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2020/V34/I6/565

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Research progress of non-coding RNA in bladder cancer

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