Abstract: Objective We intend to explore the best solution of colorectal cancer screening to achieve early detect,early diagnosis and early therapy for colorectal neoplasm by analyzing the Results of colorectal screening in Haicang District of Xiamen City.Methods From Dec.2008 to Oct.2010,preliminary screening was carried out to the inhabitants arranging from 40 to 74 years old in 4 villases of Haicang District combining questionnaires and continuous fecal occult blood test(FOBT),which is recommended by Chinese Cancer Fundation.High risk people accepted complete colonoscopy.Total number is 8179 people,among which 6380 people actually received screening.Results 81.06 percent of 1035 high risk people obtained by questionnaires and FOBT accepted complete colonoscopy.Positive incidence of colorectal cancer,adenomatous polyps and other lesions were 1.67% and 23.96% respectively.Colorectal cancer detection rate was significantly higher in questionnaires and FOBT were both positive than in questionnaire or FOBT positive alone(P＜0.05).Colorectal cancer detection rate was significantly higher in FOBT twice positive than in FOBT negative or FOBT once positive(P＜0.05).Significant linear relationship was observed between times of detection rate in FOBT positive and colorectal cancer and adenomatous polyps and other lesions detection rate(P＜0.05).Conclusion Combining questionnaires and continuous FOBT can significantly concentrate high-risk group colorectal cancer,therefore can greatly reduce the workload of screening.

Key words: Colorectal cancer, Screening, Fecal occult blood test, Questionnaire