紫云英苷抗肿瘤作用相关信号通路的研究进展

doi:10.11904/j.issn.1002-3070.2024.01.010

Abstract

Abstract: Astragalin is a natural flavonoid,which is known for its diverse pharmacological applications such as anti-tumor.The many studies have found that Astragalin has great anti-tumor potential by regulating PI3K/Akt signal pathway,MAPKs signal pathway,JAK/STAT signal pathway,NF-κ B signal pathway,Notch1 pathway,microRNA expression,tumor invasion and metastasis.This article reviews the literature reports on anti-tumor signal pathway of Astragalin in recent years,analyzes and summarizes the possible mechanisms by which each pathway induces tumor cell apoptosis,in order to provide experimental and theoretical basis for the development and utilization of Astragalin in anti-tumor signal pathways.

Key words: Astragalin, Anti-tumor, Signaling pathway

CLC Number:

R285

XIAO Ding, BAI Juncheng, ZHANG Bin. Research progress of signal pathways related to the anti-tumor effect of Astragalin[J]. Journal of Practical Oncology, 2024, 38(1): 62-66.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2024.01.010

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Research progress of signal pathways related to the anti-tumor effect of Astragalin

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