PRACTICAL ONCOLOGY JOURNAL ›› 2015, Vol. 29 ›› Issue (3): 275-278.doi: 10.11904/j.issn.1002-3070.2015.03.019

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The gene expression profile in the pathological diagnosis and differential diagnosis of tumors

LI Ruyi,LU Jianbo   

  1. Department of Pathology,The First Affiliated Hospital of Kunming Medical University,Kunming 650032,China
  • Received:2013-02-15 Online:2015-06-28 Published:2015-06-25

Abstract:

Through analyzing the gene expression profile of tumor cells with gene chip technology and selecting the differentially expressed genes of different tumor individuals and tumor types,researchers find that these genes are not only connected with tumor growth,proliferation,apoptosis,and signal transduction,but also with tumor pathogenesis,tumor infiltration,tumor metastasis and tumor drug resistance.Some tumor differentially expressed genes or genomes show that these genes are even associated with tumor histological source and histological type.It demonstrates practical application value in the pathological diagnosis and differential diagnosis of tumors.

Key words: Gene expression profiling, Nasopharyngeal carcinoma, Lung carcinoma, Gastric cancer, Colorectal cancer

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