FAK在恶性肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2016.02.015

Abstract

Abstract: Focal adhesion kinase(FAK),a cytoplasmic non-receptor protein tyrosine kinase,serves as both a molecular scaffold and a mediator participating in multiple signal transduction pathways.FAK is involved in tumor cell survival,proliferation,migration and metastasis.Recent studies have shown that FAK is expressed in many tumor cells.Currently,FAK has been regarded as a potential target for cancer therapy.This review is to summarize the relationship between FAK and tumor progression.

Key words: Focal adhesion kinase, Cancer, Signal pathway

CLC Number:

ZHAO Meina, CHEN Gongyan. Research progress on focal adhesion kinase in malignant tumors[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(2): 162-166.

References

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Research progress on focal adhesion kinase in malignant tumors

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