1 Hu CM,Jang SY,Fanzo JC,et al.Modulation of T cell cytokine production by interferon regulatory factor-4[J].J Biol Chem,2002,277(51):49238-49246. 2 Shu CL,Jing YL,Su LC,et al.SWAP-70:a new type of oncogene[J].PLoS One,2013,8(3):e4422. 3 Gupta S,Lee A,Hu C,et al.Molecular cloning of IBP,a SWAP-70 homologous GEF,which is highly expressed in the immune system[J].Hum Immunol,2003,64(4):389-401. 4 Liu JJ,Lin M,Yu JY,et al.Targeting apoptotic and autophagic pathways for cancer therapeutics[J].Cancer Lett,2011,300(2):105-114. 5 Lazer G,Katzav S.Guanine nucleotide exchange factors for RhoGTPases:good therapeutic targets for cancer therapy?[J].Cell Signal,2011,23(23):969-979. 6 Srougi MC,Burridge K.The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage[J].PLoS One,2011,6(2):e17108. 7 Chen Q,Gupta S,Pernis AB.Regulation of TLR4-mediated signaling by IBP/Def6,a novel activator of Rho GTPases[J].J Leukoc Biol,2009,85(3):539-543. 8 Goudevenou K,Martin P,Yeh YJ,et al.Def6 is required for convergent extension movements during zebrafish gastrulation downstream of Wnt5b signaling[J].PLoS One,2011,6(10):e65. 9 Burgess DJ.Breast cancer:circulating and dynamic EMT[J].Nat Rev Cancer,2013,13(3):148-149. 10 Peng L,Zhang Z,Wang Q,et al.The ectopic expression of IFN regulatory factor 4-binding protein is correlated with the malignant behavior of human breast cancer cells[J].Int Immunopharmacol,2009,9(7/8):1002-1009. 11 Yang M,Fang Y,Peng L,et al.Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells[J].Mol Cancer,2011,11(1):1-13. 12 Chen S,Han Q,Wang X,et al.IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway[J].Cell Death Dis,2013,4(10):377-377. 13 杨明珍.乳腺癌中IBP的转录调控机制及其意义的初步研究[D].北京:第三军医大学,2012. 14 Zhang Z,Wang Q,Peng L,et al.Overexpression of the interferon regulatory factor 4-binding protein in human colorectal cancer and its clinical significance[J].Cancer Epidemiol,2009,33(2):130-136. 15 Vistica BP,Shi G,Nugent L,et al.SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis(EAU)[J].Mol Vis,2012,18(192):1858-1864. 16 何颖,张竹君.IBP通过上皮间质转化促进结肠癌细胞迁移和侵袭[J].第三军医大学学报,2016,38(11):1281-1285. 17 Tiwari N,Gheldof A,Tatari M,et al.EMT as the ultimate survival mechanism of cancer cells[J].Semi in Cancer Biol,2012,22(22):194-207. 18 张竹君.特异性IRF-4结合蛋白(IBP)多克隆抗体制备及其在人结肠癌中表达模式的初步研究[D].北京:第三军医大学,2009. 19 Gulhati P,Bowen KA,Liu J,et al.MTORC1 and mTORC2 regulate EMT,motility,and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways[J].Cancer Res,2011,71(9):3246-3256. 20 Chang YJ,Cheng YW,Lin RK,et al.Thrombomodulin influences the survival of patients with non-metastatic colorectal cancer through epithelial-to-mesenchymal transition(EMT)[J].PLoS One,2016,11(8):e0160550. 21 Shuman Moss LA,Jensen-Taubman S,Stetler-Stevenson WG.Matrix metalloproteinases:changing roles in tumor progression and metastasis[J].Am J of Pathol,2012,181(6):1895-1899. 22 简从相,黄晓山,李晨军.IRF-4结合蛋白在口腔鳞癌中的表达及临床意义[J].实用口腔医学杂志,2012,28(4):478-481. 23 潘磊,简从相,李卓,等.IRF-4结合蛋白对口腔鳞癌细胞生长作用的机制研究[J].西南国防医药,2014,24(5):468-470. 24 石俊婷,赵凌,蔡双兵,等.IBP对口腔鳞癌增殖作用的体内研究[J].西南国防医药,2014,24(9):951-953. 25 熊剑,简从相,李鹏,等.IRF-4结合蛋白对人涎腺腺样囊性癌细胞增殖的抑制作用[J].第三军医大学学报,2011,33(6):554-557. 26 熊剑.IBP(IRF-4结合蛋白)在人涎腺腺样囊性癌中表达及功能的实验研究[D].北京:第三军医大学,2011. 27 Ishii K,Shimoda M,Sugiura T,et al.Involvement of epithelial-mesenchymal transition in adenoid cystic carcinoma metastasis[J].Int J Oncol,2011,38(4):921-931. 28 Radisky DC,Levy DD,Littlepage LE,et al.Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability[J].Nature,2005,436(7047):123-127. 29 熊剑,常慧君,李鹏,等.IBP促进人涎腺腺样囊性癌细胞对紫杉醇耐药[J].第三军医大学学报,2012,34(8):723-725. |