铁皮石斛抑制上皮源性恶性肿瘤的研究进展

doi:10.11904/j.issn.1002-3070.2020.04.013

Abstract

Abstract: Dendrobium officinale,as a traditional Chinese medicinal material in China,has the effects of reversing oxidation,anti-fatigue,regulating immunity and reducing blood sugar.In recent years,the role of dendrobium officinale in antitumor has attracted widespread attention.The results from many studies show that dendrobium officinale can act on the inhibitory effects on epithelial-derived malignant tumors through a variety of mechanisms or pathways.The growth of epithelial-derived malignant tumors can be inhibited by regulating DNA damage,reducing the expression of inflammatory factors and other ways to prevent cancer,block cancer cell cycle,inhibit tumor angiogenesis,and induce cancer cell apoptosis ways.Compared with the serious toxic and side effects of chemoradiotherapy drugs,dendrobium officinale is more natural and safer,which makes the innovation of new drug and product of dendrobium officinale have broad prospects.Based on a large amount of research data from the inhibition of epithelial-derived malignant tumors by dendrobium officinale,this paper reviews a large number of domestic and foreign research advances,and provides a basis for further development and application of dendrobium officinale.

Key words: Dendrobium officinale, Cancer, Inhibitory effect, Apoptosis

CLC Number:

PANG Chen, ZHANG Xiuling, ZHANG Xiliu. Research progress in inhibitory epithelium-derived malignant tumors by dendrobium officinale[J]. Journal of Practical Oncology, 2020, 34(4): 362-367.

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Research progress in inhibitory epithelium-derived malignant tumors by dendrobium officinale

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